Themes and summary (AI-generated based on podcaster-provided show and episode descriptions):
➤ expert interviews on breakthrough research•brain, behavior, mindfulness, grief, aging•medical tech: imaging, bioelectronics, drugs, microplastics, vaccines•AI, quantum sensing/biology, wearables•space, climate, economics, social policy
This podcast features long-form conversations with researchers and other subject-matter experts about work that is reshaping how we understand people, health, technology, and the wider world. Episodes generally translate complex scholarship into accessible explanations, often pairing a clear account of the underlying science or evidence with discussion of real-world implications, ethical tensions, and what remains unknown.
A major throughline is the human mind and behavior. The show frequently examines how we form a sense of self, why people get “stuck” and how behavior changes, how language influences decisions, what makes experiences memorable, and how grief affects both psychology and physiology. It also revisits contested ideas in mental health and cognition, including debates about psychiatric labels, the challenges of treating brain disorders, and how neurodegenerative diseases can alter personality and social behavior. Related conversations explore wellbeing more broadly, such as different dimensions of a “good life,” the cognitive effects of nature exposure, and research on mindfulness and mind–body interactions.
Another recurring focus is emerging biomedical and bioengineering innovation. Topics include advances in imaging and sensing (from next-generation MRI to quantum and biologically inspired sensors), bioelectronics and bioelectricity as tools for healing and regeneration, the promise and limits of pharmaceuticals and drug regulation, and public health questions such as vaccine hesitancy, alcohol risk, microplastics exposure, and the potential for future fungal outbreaks. Aging and longevity research appears often, spanning cellular mechanisms, exceptional cognitive aging, and what animal studies can reveal about lifespan and healthspan.
Technology and society is a third pillar. The podcast explores artificial intelligence’s impact in domains like medicine, law, art, and scientific discovery, including concerns about “human-like” AI, the governance of rapidly advancing models, and tools designed to protect creative work from AI scraping. Social science episodes address inequality and policy-relevant issues—parenting and child development, fertility and non-motherhood, housing and race, gun violence prevention, youth political attitudes, and how genetics may intersect with social outcomes.
Finally, the show regularly turns outward to big-picture science, including planetary habitability, the search for life beyond Earth, Mars’s past and potential futures, disputed measurements of the universe’s expansion, and the science of death and resuscitation.
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Episodes:
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Can You Improve Your Working Memory and Attention? with Edward Awh
2026-Feb-05
35 minutes
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Why Knowing Your True Self Is So Difficult, with Eric Oliver
2026-Jan-22
31 minutes
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The Breakthrough Quantum Sensor That Sees Inside Your Cells, with Peter Maurer
2026-Jan-08
35 minutes
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How to Manifest Your Destiny with the Late James Doty
2025-Dec-29
31 minutes
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What Makes Music Go Viral—From AI to Taylor Swift
2025-Dec-11
35 minutes
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How Wearable Tech Will Heighten Our Senses and Abilities, with Pedro Lopes
2025-Nov-24
38 minutes
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Why Are More Women Saying No To Having Kids? With Peggy O'Donnell Heffington
2025-Nov-13
32 minutes
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How Full-Body MRIs Could Predict Your Long-Term Health, with Daniel Sodickson
2025-Oct-30
34 minutes
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Is There Such A Thing As A Psychopath?
2025-Oct-16
35 minutes
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Why We Haven’t Solved Brain Disorders—And How To Fix It, with Nicole Rust
2025-Oct-02
36 minutes
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Life On Mars: Is It Possible For Humans? with Edwin Kite
2025-Sep-19
30 minutes
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How To Use Nature To Restore Your Focus, with Marc Berman
2025-Sep-04
32 minutes
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Could Plants Unlock Quantum Medicine’s Potential? with Greg Engel
2025-Aug-21
25 minutes
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How Microplastics Are Invading Our Bodies, with Matthew Campen
2025-Aug-07
28 minutes
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Why We Get Stuck—And How to Finally Move Forward
2025-Jul-24
34 minutes
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Inside the AI Debate: Hope, Hype, Or Harm? A Big Brains Panel Weighs In
2025-Jul-10
47 minutes
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Are Your Medications Safe And Effective?, with Jerry Avorn
2025-Jun-26
36 minutes
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Are We Making AI Too Human?, with James Evans
2025-Jun-12
31 minutes
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Inside The Disease That Changes Your Personality, with Bruce Miller
2025-May-29
26 minutes
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Meet The ‘Planet Hunter’ Searching For Alien Life, with Jacob Bean
2025-May-15
34 minutes
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How To Stop Gun Violence Before It Starts, with Jens Ludwig
2025-May-01
30 minutes
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Can Your DNA Predict Your Future?, with Dalton Conley
2025-Apr-17
34 minutes
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Can You Really Die of a Broken Heart? The Hidden Dangers of Grief, with Mary Frances O'Connor
2025-Apr-03
31 minutes
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The Science Behind Raising Successful Kids, with Ariel Kalil
2025-Mar-20
31 minutes
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Do Animals Understand Death?, with Susana Monsó
2025-Mar-06
32 minutes
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Why Measles Is Resurging—And The Rise Of Vaccine Hesitancy, with Adam Ratner
2025-Feb-20
35 minutes
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The Little-Known Secrets To A Good Life, with Shigehiro Oishi
2025-Feb-06
33 minutes
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How Bioelectronics Could Heal Our Bodies And Minds, with Bozhi Tian
2025-Jan-23
29 minutes
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Could A Fungal Pandemic Be “The Last of Us?", with Arturo Casadevall
2025-Jan-09
27 minutes
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The "Magic Words" That Turn Resolutions Into Reality
2025-Jan-02
32 minutes
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What’s The Truth About Alcohol’s Benefits And Risks? with Tim Stockwell
2024-Dec-19
33 minutes
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What Happens When We Die? with Sam Parnia
2024-Dec-05
30 minutes
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The Illusion of Moral Decline
2024-Nov-21
32 minutes
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Can We Predict The Unpredictable? with J. Doyne Farmer
2024-Nov-14
33 minutes
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Unlocking The Secrets Of ‘SuperAgers’, with Emily Rogalski
2024-Oct-31
22 minutes
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2024 Nobel Laureate Explains What Makes Countries Fail Or Succeed, with James A. Robinson
2024-Oct-17
29 minutes
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Why Can’t Scientists Agree On The Age Of The Universe? with Wendy Freedman
2024-Oct-03
24 minutes
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What Are We Getting Wrong About Young Voters?, with Cathy Cohen
2024-Sep-19
28 minutes
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Why Are More Women Saying No To Having Kids? With Peggy O'Donnell Heffington
2024-Sep-05
32 minutes
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How Homeownership Shaped Race In America, with Adrienne Brown
2024-Aug-22
27 minutes
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Fighting Back Against AI Piracy, with Ben Zhao and Heather Zheng
2024-Aug-08
28 minutes
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The Bioelectric Future of Regenerative Medicine
2024-Jul-25
28 minutes
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Is Mindfulness The Secret To Health?
2024-Jul-11
33 minutes
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Feeling Stuck? Here’s How To Achieve a Breakthrough, with Adam Alter
2024-Jun-27
33 minutes
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What Makes Something Memorable (or Forgettable?) with Wilma Bainbridge
2024-Jun-13
26 minutes
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Learning To Speak To Whales Using AI, with David Gruber
2024-May-30
26 minutes
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Storm Warning: Why Hurricanes Are Growing Beyond Measure, with Michael Wehner
2024-May-16
27 minutes
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How To Manifest Your Future Using Neuroscience, with James Doty
2024-May-02
31 minutes
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Why We Die—And How We Can Live Longer, with Nobel Laureate Venki Ramakrishnan
2024-Apr-18
32 minutes
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What Dogs Are Teaching Us About Aging, with Daniel Promislow
2024-Apr-04
32 minutes
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Where Has Alzheimer’s Research Gone Wrong? with Karl Herrup
2024-Mar-21
29 minutes
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Why Breeding Millions of Mosquitoes Could Help Save Lives, With Scott O'Neill
2024-Mar-07
30 minutes
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Why Shaming Other Countries Often Backfires, with Rochelle Terman
2024-Feb-22
33 minutes
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Can Trump Legally Be President?, with William Baude
2024-Feb-06
36 minutes
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What Our Hand Gestures Reveal About Our Thoughts, with Susan Goldin-Meadow
2024-Jan-25
26 minutes
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Psychedelics Without Hallucinations: A New Mental Health Treatment? with David E. Olson
2024-Jan-11
32 minutes
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The Science Of Happiness
2023-Dec-28
29 minutes
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Do We Really Have Free Will? With Robert Sapolsky
2023-Dec-14
34 minutes
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A Radical Solution To Address Climate Change, with David Keith
2023-Nov-30
33 minutes
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How PFAS “Forever Chemicals” Are Harming Our Health, with Linda Birnbaum
2023-Nov-16
29 minutes
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Are We Worse People Than We Used To Be? With Adam Mastroianni
2023-Nov-02
31 minutes
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Freakonomics’ Steven Levitt On The Secret To Making Tough Choices
2023-Oct-19
39 minutes
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Will Political Violence Destroy Our Democracy?, With Robert Pape
2023-Oct-05
28 minutes
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Defending Campus Free Speech In A Polarized Age, with Paul Alivisatos and Tom Ginsburg
2023-Sep-22
32 minutes
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Why The Secret To Health Lies In The Mind-body Connection, with Ellen Langer
2023-Sep-07
32 minutes
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Phonics Vs. Whole Word: The Science Of Reading, With Adrian Johns
2023-Aug-24
34 minutes
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How AI Is Transforming Scientific Research, With Rebecca Willett
2023-Aug-10
31 minutes
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How AI Could Change The Law
2023-Jul-27
27 minutes
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How AI Can Predict Future Scientific Discoveries
2023-Jul-20
29 minutes
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The Uncovered History of Space Travel & Its Privatized Future
2023-Jul-13
28 minutes
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The Health Costs of Air Pollution
2023-Jul-06
28 minutes
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How Your Brain Benefits From Music, With Larry Sherman
2023-Jun-29
29 minutes
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Magic words: Can What You Say Help You Get Your way? with Jonah Berger
2023-Jun-15
31 minutes
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Providing Basic Health Insurance For Every American, With Katherine Baicker
2023-Jun-01
31 minutes
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Why We Fight, With Christopher Blattman
2023-May-25
28 minutes
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The Hidden Truths About Sexuality And Gender In The Medieval World, with Roland Betancourt
2023-May-11
29 minutes
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How We Could Regrow Limbs And Organs, with Michael Levin
2023-Apr-27
28 minutes
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A Nobelist’s Controversial Approach To Solving Inequality, With James Heckman
2023-Apr-13
32 minutes
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How The Food Industry Created Today’s Obesity Crisis, With Marion Nestle
2023-Mar-30
31 minutes
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Why Your Gut Health Is So Important, With Cathryn Nagler And Eric Pamer
2023-Mar-16
34 minutes
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Why Mourning Is Essential To Our Well-Being, With Jonathan Lear
2023-Mar-02
25 minutes
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The History of Black Cinema Re-examined, With Jacqueline Stewart
2023-Feb-16
32 minutes
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The Scientific Secret To A Happy Life, With Marc Schulz
2023-Feb-02
29 minutes
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Unraveling Sleep’s Greatest Mysteries: The Day Tomorrow Began
2023-Jan-19
34 minutes
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Is The U.S. Headed Toward Another Civil War? Feat. William Howell
2023-Jan-05
30 minutes
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Follow Through On Next Year's Resolutions Using Science With Katy Milkman
2022-Dec-22
28 minutes
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Why Quantum Tech Will Change Our Future: The Day Tomorrow Began
2022-Dec-08
28 minutes
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Fighting Global Hunger Through Genetics With Chuan He
2022-Nov-24
23 minutes
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The Origins Of Civilization And The Future Of Archaeology: The Day Tomorrow Began
2022-Nov-10
35 minutes
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Can We Predict Your Capacity To Focus? With Monica Rosenberg
2022-Oct-28
27 minutes
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The 'Legendary' Discovery Of Black Holes: The Day Tomorrow Began
2022-Oct-13
35 minutes
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Celebrating Our 100th Episode
2022-Sep-29
17 minutes
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The Science Of Speech & Identity With Katherine Kinzler
2022-Sep-22
31 minutes
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Life’s Mysterious Origins With Jack Szostak
2022-Sep-15
22 minutes
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The Afterlife Of Mass Incarceration With Reuben Jonathan Miller
2022-Sep-08
36 minutes
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The Imbalance In Our Society With Raghuram Rajan
2022-Sep-01
25 minutes
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Does Welfare Reduce Crime? With Manasi Deshpande
2022-Aug-18
27 minutes
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The Crucial Race To Build A Better Battery With Shirley Meng
2022-Aug-04
26 minutes
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Do Animals Dream? With David M. Peña-Guzmán
2022-Jul-21
33 minutes
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Extreme Heat Waves: Why Are They Surging? with Noboru Nakamura
2022-Jul-07
22 minutes
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Why Air Pollution Is Cutting Years Off Our Lives, With Christa Hasenkopf And Anant Sudarshan
2022-Jun-23
28 minutes
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How Tax Dodging And Corporate Secrecy Found A Home In Delaware, With Hal Weitzman
2022-Jun-09
32 minutes
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Why Countries Choose War Over Peace, With Chris Blattman
2022-May-26
29 minutes
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How Death In America Is Changing With Shannon Lee Dawdy
2022-May-12
26 minutes
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Why We Need To Invest In Parents During A Child's Earliest Years, With Dana Suskind
2022-Apr-28
25 minutes
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The Troubling Rise Of Antibiotic-resistant Superbugs, With Christopher Murray
2022-Apr-14
23 minutes
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Is Scientific Progress Slowing? with James Evans
2022-Mar-31
29 minutes
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Could We Vaccinate Against Opioid Addiction? With Sandra Comer And Marco Pravetoni
2022-Mar-17
24 minutes
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The Man Who Fought To Sanction Putin And Russian Oligarchs, with Bill Browder
2022-Mar-02
31 minutes
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Why Big Ideas Fail To Scale—And How To Fix It With John List
2022-Feb-17
28 minutes
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Could Personalizing Laws Make Society More Just? With Omri Ben-Shahar
2022-Feb-03
26 minutes
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How To Stick To Your Resolutions, With Ayelet Fishbach
2022-Jan-20
28 minutes
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The Overlooked History Of Black Cinema, With Jacqueline Stewart
2022-Jan-06
31 minutes
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Engineering A Cure For Cancer With Melody Swartz & Jeffrey Hubbell
2021-Dec-23
26 minutes
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Confronting Gun Violence With Data, With Jens Ludwig
2021-Dec-09
39 minutes
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Best Of: Why Talking to Strangers Will Make You Happier With Nicholas Epley
2021-Dec-02
25 minutes
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Unlocking The Secrets Of Black Holes, With Andrea Ghez
2021-Nov-18
28 minutes
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Do Your Genes Determine Your Success In Life? With Kathryn Paige Harden
2021-Nov-04
29 minutes
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How The UN Aims To Save Humanity, With Chris Williams And Luis Bettencourt
2021-Oct-21
25 minutes
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Combating Our Global Water Crisis Using AI, with Junhong Chen
2021-Oct-07
25 minutes
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Revolutionizing Technology at the Nanoscale, with Paul Alivisatos
2021-Sep-23
26 minutes
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The Science Behind Forming Better Habits, With Katy Milkman
2021-Sep-09
27 minutes
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The Secret Nazi Past and Billionaire Future of U.S. Space Innovation with Jordan Bimm
2021-Aug-19
27 minutes
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How a Genetic Breakthrough Could Address Global Hunger
2021-Aug-05
22 minutes
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Introducing: Entitled
2021-Jul-29
41 minutes
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The Deadly Flaw In Our Judgment, With Cass Sunstein
2021-Jul-15
25 minutes
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A Scientist’s Beef With The Meat Industry, With Impossible Foods’ Pat Brown
2021-Jul-01
23 minutes
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A Surprising Economic Solution To Climate Change With Michael Greenstone
2021-Jun-17
25 minutes
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Solving The Biggest Mysteries Of Our Universe, With Dan Hooper
2021-Jun-03
29 minutes
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Why You’re Likely Paying An Unfair Share of Property Taxes, with Christopher Berry
2021-May-20
29 minutes
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Taking Aliens Seriously, with Avi Loeb
2021-May-06
32 minutes
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The ‘Five Horsemen of the Techpocalypse’ with Kara Swisher
2021-Apr-22
23 minutes
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Fighting Poverty And Pandemics, with Nobel Economist Michael Kremer
2021-Apr-08
31 minutes
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Why Life After Incarceration Is Just Another Prison, with Reuben Jonathan Miller
2021-Mar-25
36 minutes
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Anthony Fauci On What We Need To Get Over COVID-19
2021-Mar-08
28 minutes
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The Ethics of COVID-19 Vaccine Distribution, with Laurie Zoloth
2021-Feb-25
32 minutes
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The Doomsday Clock’s ‘Historic Wake-Up Call,’ With Rachel Bronson
2021-Feb-11
34 minutes
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Unraveling the Mystery of Life’s Origins on Earth, with Jack Szostak
2021-Jan-28
21 minutes
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The Urgent Need to Reinvest in American Research, with Barbara Snyder
2021-Jan-14
26 minutes
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Getting Out Of The Lab With John List
2020-Dec-22
27 minutes
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How Alternate Reality Games Are Changing The Real World with Patrick Jagoda and Kristen Schilt
2020-Dec-10
32 minutes
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The Science of Empathy, with Peggy Mason
2020-Nov-25
20 minutes
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Big Brains Presents: The "Capitalisn't" Podcast
2020-Nov-20
47 minutes
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What Remains Unanswered After The 2020 Election, with William Howell and Luigi Zingales
2020-Nov-11
34 minutes
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When Governments Share Their Secrets—And When They Don't, with Austin Carson
2020-Oct-29
28 minutes
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How We Can Fix a Fractured Supreme Court, with Geoffrey Stone
2020-Oct-15
25 minutes
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Correcting History: Native Americans Tell Their Own Stories
2020-Oct-01
36 minutes
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The Future of Voting And The 2020 Election, with Anthony Fowler
2020-Sep-17
24 minutes
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Why The Quantum Internet Could Change Everything, with David Awschalom
2020-Sep-03
25 minutes
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How Loneliness and Isolation Affect Your Health, with Prof. Linda Waite
2020-Aug-27
23 minutes
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The Way You Talk—And What It Says About You, with Prof. Katherine Kinzler
2020-Aug-13
30 minutes
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From LSD to Ecstasy, How Psychedelics Are Altering Therapy, with Prof. Harriet de Wit
2020-Jul-30
19 minutes
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How Can We Achieve Real Police Reform?
2020-Jul-16
30 minutes
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Why We're Obsessed With Conspiracy Theories
2020-Jul-02
27 minutes
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Black Lives Matter Protests: Hope for the Future?
2020-Jun-18
40 minutes
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What Historic Pandemics Could Teach Us About Coronavirus, with Ada Palmer
2020-Jun-08
29 minutes
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A Crisis Management Expert’s Advice on Handling Coronavirus
2020-May-21
27 minutes
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How Students and Schools Can Recover From Coronavirus, with Elaine Allensworth
2020-May-12
19 minutes
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Trump, Coronavirus and the Cost of Ineffective Government, With William Howell
2020-Apr-30
27 minutes
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How Coronavirus Is Exposing Our Racial Disparities, with Monica Peek
2020-Apr-21
17 minutes
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Coronavirus Shows Why We Need To Rethink Health Care, with Kate Baicker
2020-Apr-03
15 minutes
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What Rats Can Teach Us About Empathy and Racism, with Peggy Mason
2020-Mar-10
20 minutes
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Why the Coronavirus Could Send China’s Economy Back to the 1980s With Chang-Tai Hsieh
2020-Feb-25
18 minutes
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Why The Doomsday Clock Is Closer To Apocalypse Than Ever With Rachel Bronson
2020-Feb-12
25 minutes
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Vladimir Putin’s Number One Enemy With Bill Browder
2020-Jan-27
25 minutes
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How Google and Facebook Are Ruining Capitalism, with Luigi Zingales
2020-Jan-13
26 minutes
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How Quantum Technology Could Change Our Future With David Awschalom
2019-Dec-30
19 minutes
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The Myths Of Millennial Voters With Cathy Cohen
2019-Dec-16
20 minutes
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Why Some Nations Prosper and Others Fail, with James Robinson
2019-Dec-02
27 minutes
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The Hunt for Alien Life and Exoplanets, with David Charbonneau
2019-Nov-18
21 minutes
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Why Chasing The Good Life Is Holding Us Back With Lauren Berlant
2019-Nov-04
24 minutes
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Saving Our Cities By Studying A Million Neighborhoods With Luis Bettencourt
2019-Oct-23
23 minutes
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Why Talking to Strangers Will Make You Happier With Nicholas Epley
2019-Oct-07
24 minutes
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Leading Presidential Scholar Analyzes Trump Impeachment
2019-Sep-27
19 minutes
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The Politics of Archaeology In Iraq With Christopher Woods
2019-Sep-23
24 minutes
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Supreme Court Justice Ruth Bader Ginsburg On Polarization, Discrimination and Her Favorite Dissent
2019-Sep-09
57 minutes
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Why Your Social Life is a Matter of Life and Death with Linda Waite
2019-Aug-26
22 minutes
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Revolutionizing Economics By Studying People In The Real World With John List
2019-Aug-12
28 minutes
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The Unknown History Of The White Power Movement With Kathleen Belew
2019-Jul-29
27 minutes
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The Missing Link In Evolution with Neil Shubin
2019-Jul-15
26 minutes
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Guest Show - No Jargon
2019-Jul-01
30 minutes
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Trump and the Changing Power of the Presidency with William Howell
2019-Jun-17
26 minutes
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How the Loss of Community Threatens Society With Raghuram Rajan
2019-Jun-03
23 minutes
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The Science of Conspiracy Theories And Political Polarization With Eric Oliver
2019-May-20
26 minutes
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A Modern Medical Miracle with Drs. Valluvan Jeevanandam and Talia Baker
2019-May-06
22 minutes
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An Archaeological Riddle In The Sahara With Paul Sereno
2019-Apr-15
26 minutes
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Tiny Creatures, Big Discoveries With Nipam Patel
2019-Apr-01
27 minutes
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The Hidden Dangers of Artificial Intelligence with Ben Zhao
2019-Mar-18
21 minutes
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Lessons From Our Country’s Largest School Closing with Eve L. Ewing
2019-Mar-04
26 minutes
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Simple Solutions To Address Social Issues with Harold Pollack
2019-Feb-18
21 minutes
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What We’re Getting Wrong About Millennials With Cathy Cohen
2019-Feb-04
20 minutes
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What Ripples in Space-Time Tell Us About the Universe with Daniel Holz
2019-Jan-21
22 minutes
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Vietnam and the Rise of the White Power Movement with Kathleen Belew
2019-Jan-07
27 minutes
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Big Brains: Back in 2019
2018-Dec-23
less than a minute
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Climate Change’s Human Cost With Michael Greenstone
2018-Dec-10
22 minutes
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David Axelrod on Why ‘Democracy is Messy’ and the Future of Politics
2018-Nov-26
25 minutes
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How Talk Builds Babies’ Brains with Dana Suskind
2018-Nov-12
21 minutes
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What Makes Us Uniquely Human with Neuroscientist Bobby Kasthuri
2018-Oct-29
24 minutes
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From Sci-Fi to Reality, Quantum Technology with David Awschalom
2018-Oct-15
21 minutes
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Future of Higher Education and College Access with Robert J. Zimmer
2018-Oct-01
34 minutes
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The Hidden Abuse of U.S. Immigration with Claudia Flores
2018-Sep-17
18 minutes
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SCOTUS Nears Unimaginable Era with Geoffrey Stone
2018-Sep-05
24 minutes
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Special University of Chicago Convocation Podcast featuring Valerie Jarrett and Marianne Bertrand
2018-Jun-12
41 minutes
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Special University of Chicago Convocation Podcast with Student Speaker Andrea Popova
2018-Jun-12
22 minutes
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Economist’s Journey to the Nobel with Richard Thaler
2018-Jun-04
44 minutes
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Future of Energy Innovation with Michael Polsky
2018-May-21
23 minutes
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The Expanding Universe with Wendy Freedman
2018-May-14
23 minutes
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Nature’s Design Secrets with Rama Ranganathan
2018-May-07
25 minutes
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Mind of a Virtuoso Composer with Augusta Read Thomas
2018-Apr-30
25 minutes
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Myths of U.S. Health Care with Katherine Baicker
2018-Apr-23
26 minutes
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Discovering the Missing Link with Neil Shubin
2018-Apr-16
27 minutes
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Big Brains Trailer
2018-Apr-05
1 minute
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